FROM BENCH TO IMPROVED PRE-HOSPITAL DIAGNOSIS OF VERY EARLY AMI: CARDIAC MYOSIN-BINDING PROTEIN C

Thomas Edward Kaier,Carsten Stengaard,Jack Marjot,Jacob Thorsted Sørensen, Stavroula Stavropoulou-Tatla,Christian Juhl Terkelsen,Luke Williams,Kristian Thygesen,Hans Erik Bøtker,Michael Marber

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2018）

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摘要

We identified Cardiac myosin binding protein C (cMyC) in coronary venous effluent and developed a high-sensitivity assay by producing an array of monoclonal antibodies and choosing an ideal pair based on affinity and epitope maps. Compared to high-sensitivity cardiac Troponin (hs-cTn), we

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