The role of Pax6 in brain development and its impact on pathogenesis of autism spectrum disorder

Takako Kikkawa,Cristine R. Casingal, Seung Hee Chun,Hiroshi Shinohara,Kotaro Hiraoka,Noriko Osumi

Brain Research（2019）

引用 31|浏览17

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摘要

•Pax6 is one of the key transcription factors in brain development.•PAX6 regulates and/or binds to hundreds of genes related to autism spectrum disorder (ASD).•PAX6/ASD-related molecules form significant clusters of molecular interactions.

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关键词

ASD,ChIP,CP,Di,dTel,EGL,GO,HB,IGL,MB,MGI,MRI,Pax,PCL,RG cells,SFARI,vTel,VZ,WAGR

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