Are metabolic disorder carries subject to poor ovarian response in PGD cycles

Introduction: Controlled ovarian hyperstimulation (COH) and expected outcome of IVF in single gene disorder patients varies significantly among women. One of our previous patient with heterozygous mutation on her GALT gene whom responded poorly to COH treatment in her repeated unsuccessful IVF attempts. She had improved results after a 3 months long galactose restricted diet which resulted in live birth. This case triggered carrying out this study with a purpose to examine the effect of being a carrier for the single gene disorder on controlled ovarian hyper stimulation (COH) treatments and the pregnancy success rate.