Synthesis of 1,2,3‐Fused Indole Polyheterocycles by Copper‐Catalyzed Cascade Reaction

A one-pot reaction has been devloped for the preparation of 1,2,3-fused indole polyheterocycles by starting from 2-iodobenzamide and 2-iodobenzyl cyanide in the presence of a copper catalyst. The cascade process involves the efficient formation of one C-C and three C-N bonds. A broad substrate scope, good yields, and short reactions times are key features of this strategy.