Label-free and competitive aptamer cytosensor based on layer-by-layer assembly of DNA-platinum nanoparticles for ultrasensitive determination of tumor cells

Yunfei Jiang,Duanping Sun,Zhixian Liang,Liang Chen,Yuanqing Zhang,Zuanguang Chen

Sensors and Actuators B: Chemical（2018）

引用 30|浏览7

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摘要

•A competitive electrochemical cytosensor was developed for detecting HepG2.•Aptamer recognition and layer-by-layer technology were well designed.•Label-free detection protected the nature property and viability of the cells.•The cytosensor performed well in sensitivity and specificity.•The electrode array-based cytosensor could be easily regenerated.

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关键词

Label-free,Electrochemical cytosensor,Layer-by-layer assembly,Aptamer,HepG2 cells,Enzyme-free

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