Electrical Stimulation, Recording and Impedance-Based Real-Time Position Detection of Cultured Neurons Using Thin-Film-Transistor Array

A novel thin-film-transistor (TFT)-based microsystem array derived from flat panel technology has been developed for functional extracellular neural stimulation and recording. These arrays are microfabricated to meet the needs of optical transparency and extremely high density of electrodes with a large sensor area over 25 mm x 27 mm. Indium tin oxide has been used for surface electrode fabricatio...