IMPROVEMENT IN SKIN DISEASE SEVERITY IS ASSOCIATED WITH REDUCED PROGRESSION OF AORTIC WALL THICKNESS IN PATIENTS WITH PSORIASIS

Jacob Groenendyk,Parag Shukla,Agastya Belur,Amit Dey,Youssef Elnabawi,Justin Rodante,Aditya Goyal,Ahmed Sadek,Navya Nanda,Mark Ahlman,Aditya Joshi,Joel Gelfand,Martin Playford,Nehal Mehta

JOURNAL OF INVESTIGATIVE MEDICINE（2018）

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摘要

Psoriasis (PSO), an inflammatory disease associated with increased subclinical atherosclerosis (ATH), provides a useful in vivo model for investigating atherogenesis. Aortic wall thickness (AWT) is known to be associated with prospective cardiovascular events. The effect of modulating skin

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