Spontaneous pregnancy after prepubertal haematopoietic cell transplantation

Spontaneous pregnancy after haematopoietic cell transplantation (HCT) is rare due to an increase incidence of premature ovarian failure resulting from pre-transplantation conditioning regimes. Increased number of long term survival of HCT patients has brought forth their fertility into focus. In this article, we reported a 34 years old woman who underwent HCT at prepubertal age and had a spontaneous pregnancy. In addition, we reviewed literature on fertility outcome in HCT survivors and the associated risk factors.