Response By Fujisawa Et Al To Letter Regarding Article, "Pulmonary Artery Denervation By Determining Targeted Ablation Sites For Treatment Of Pulmonary Arterial Hypertension"

Taishi Fujisawa,Masaharu Kataoka,Takashi Kawakami,Sarasa Isobe,Kazuaki Nakajima,Akira Kunitomi,Shin Kashimura,Yoshinori Katsumata,Takahiko Nishiyama,Takehiro Kimura,Nobuhiro Nishiyama,Yoshiyasu Aizawa,Mitsushige Murata,Keiichi Fukuda,Seiji Takatsuki

CIRCULATION-CARDIOVASCULAR INTERVENTIONS（2018）

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摘要

We appreciate the interest and comments from Drs Kuebler and Friedberg on our article.1 They pointed out that a reduction in heart rate improved right ventricular failure in an experimental model of pulmonary arterial (PA) hypertension. In addition, they suggested that tachycardia would worsen the ventricular diastolic failure and that the negative chronotropic interventions may be beneficial for ventricular function and vascular remodeling. In our patient, …

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pulmonary artery denervation,pulmonary arterial hypertension”,pulmonary artery,arterial hypertension”,targeted ablation sites

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