A Study On Differentiation Of Extra-Cardiac Activity By Slit Slat Collimation In Single Photon Emission Computed Tomography
IRANIAN JOURNAL OF NUCLEAR MEDICINE(2018)
摘要
Introduction: Myocardial perfusion SPECT by Tc-99m-Sestamibi and Tc-99m-Tetrofosmin radiopharmaceuticals usually presents a false significant increase in the radiotracer uptake in the inferior myocardium due to the uptake in organs such as liver, bowel, stomach and biliary system. The present study evaluated a suitable Slit angle for differentiating extra-cardiac activities by Slit Slat collimation.Methods: The Siemens E.CAM gamma camera equipped with a Low Energy High Resolution (LEHR) collimator was simulated with the Simulating Medical Imaging Nuclear Detectors (SIMIND) Monte Carlo program. Following the verification of the simulation, a Slit Slat collimator was simulated for SPECT imaging of a NURBS-based Cardiac Torso (NCAT) phantom with different Slit angels ranged from 0 to 30 degrees. The reconstructed images were qualitatively assessed with blinded observer method by three nuclear medicine specialists.Results: The improved differentiation of the bowel activity from the cardiac was obtained by a Slit-Slat collimator with the Slit angle of 7 degree. While for gastric activity differentiation an angle of 15 degree for the Slit was useful.Conclusion: The results showed that Slit Slat collimation with 7 and 15 Slit angle provide a suitable differentiation of the bowel and gastric activities from the cardia, respectively.
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关键词
Myocardium, NCAT, SPECT, Slit Slat collimator, SIMIND Monte Carlo
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