Decision Making Alteration And Characteristic Connectivity Changes In Amyotrophic Lateral Sclerosis

Kazunori Imai,Michihito Masuda,Hazuki Watanabe,K. Kamagata, K. Katahira,Aya Ogura,Reiko Ohdake,Kazuya Kawabata,T. Yokoi,Kazuhiro Hara,Epifanio Bagarinao,Naoki Atsuta,Ryoichi Nakamura,S. Aoki,Masahisa Katsuno,H. Ohira,Gen Sobue

JOURNAL OF THE NEUROLOGICAL SCIENCES（2017）

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摘要

Background: Increasing evidence suggests clinical and pathological overlap in frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). We have reported that caudate and its networks were the most vulnerable lesion in sporadic ALS-FTLD-spectrum patients associated with cognitive decline.

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关键词

amyotrophic lateral sclerosis,characteristic connectivity changes,decision making

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