P2.07-009 Monitoring Nivolumab Binding as a Method to Clarify the Residual Therapeutic Effects in Previously Treated Lung Cancer Patients

A. Osa,S. Koyama, T. Uenami, K. Fujimoto,Y. Naito,H. Hirata,T. Takimoto,I. Nagatomo, Y. Takeda,H. Kida, M. Mori, T. Kijima,A. Kumanogoh

JOURNAL OF THORACIC ONCOLOGY(2017)

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摘要
Although the biological durability of Nivolumab, the PD-1 blocking antibody, was reported to continue longer than 12 weeks, the maximum duration of its efficacy, along with toxicity, after discontinuation and the correlation between residual binding and clinical events in cases of sequential therapeutic regimens remain unclear.
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关键词
Nivolumab,residual binding,immune profiling
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