Ultrasensitive electrochemical paper-based biosensor for microRNA via strand displacement reaction and metal-organic frameworks

He Wang, Yannan Jian,Qingkun Kong,Haiyun Liu,Feifei Lan,Linlin Liang,Shenguang Ge,Jinghua Yu

Sensors and Actuators B: Chemical（2018）

引用 119|浏览28

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摘要

•Au nanoparticles and Cu-MOFs cooperatively catalyze the oxidation of glucose.•The target initiates strand displacement reaction cycle for signal amplification.•An origami electrochemical device with portable owns extremely high sensitivity.

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关键词

MicroRNA,Origami electrochemical device,Signal amplification,Cu-based metal-organic frameworks,Stand displacement reaction

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