Structural changes on polymeric nanoparticles induced by hydrophobic drug entrapment

Colloids and Surfaces A: Physicochemical and Engineering Aspects(2018)

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摘要
Several scattering techniques (DLS, SLS, SAXS) and transmission electron microscopy (TEM, cryo-TEM) were used to probe how the entrapment of a hydrophobic drug molecule modifies the inner structure of polyester nanoparticles.
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PBSBDL,PLA,PLGA,RG,RH,ρ,PTX,d,dNP,R,PBS,PBDL,Mn,Mw,Mw/Mn,BS,BDL,B,ϕwater,Mw(NP),p(r),ζ,χ,δ
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