The Protective Effect of Maluodan against Chronic Gastritis

Objective To explore the protective effect of the Maluodan Honey Pill (MHP) to chronic gastritis. Methods The effects of gastric emptying and intestinal propulsion effects were observed by charcoal method. The ligation of pylorus was applied to investigate the effect of acid suppression. Results During gastric emptying and intestinal propulsion experiments, the MHP groups (7 mg/kg/d or 3.5 mg/kg/d) had significant difference compared with the blank control group (P u003c 0.01). The gastric residual rate was decreased significantly in MHP-H and MHP-L groups, while the intestinal residual rate was increased significantly. Compared with the blank control group, the value of pH on gastric juice significantly increased in MHP groups (P u003c 0.01). The total acidity of gastric juice significantly decreased in MHP group (7 mg/kg/d or 3.5 mg/kg/d) compared with the blank control group (P u003c 0.01). Conclusion The protective effect of MHP to chronic gastritis was performed via promoting of gastric emptying, intestinal propulsion and acid suppression.