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08.24 Monoclonal acpa antibodies recognising a common citrulline motif are mainly dependent on light chain hypermutations for antigen recognition

Johanna Steen,Björn Forsström,Lena Israelsson,Akilan Krishnamurthy,Monika Hansson,Peter Sahlström,Ragnhild Stålesen,Victoria Odowd,Stephen Edward Rapecki,Lars Klareskog,Anca Irinel Catrina,Peter Nilsson,Daniel John Lightwood,Vivianne Malmström

ANNALS OF THE RHEUMATIC DISEASES（2017）

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摘要
MONOCLONAL ACPA ANTIBODIES RECOGNISING A COMMON CITRULLINE MOTIF ARE MAINLY DEPENDENT ON LIGHT CHAIN HYPERMUTATIONS FOR ANTIGEN RECOGNITION
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