Triterpenoid saponins from Clematis chinensis and their inhibitory activities on NO production

Qiang Fu,Lu Qiu,Hai-Mei Yuan,Yu-Feng Du,Xiao-Ling Cheng,Ting-Ting Tang,Ping Wang,Ling Xu,Jun-Ming Liang,Long-Fei Yang,Liang Zou,Shu-Yun Xu

Phytochemistry Letters（2017）

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摘要

•21α-hydroxyoleanolic acid type saponins from the roots and rhizomes of Clematis chinensis were studied.•Four new compounds were isolated.•Their structures were elucidated on the basis of spectroscopic evidence.•Inhibitory effects against NO production in LPS-induced RAW 246.7 macrophages were investigated.

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关键词

Triterpenoid saponins,Clematis chinensis,Anti-inflammatory activity,Nitric oxide production

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