Aging Related White Matter Tracts Detection Based on 42 Clinically Healthy Subjects

Diffusion tensor imaging (DTI) offers an efficient evaluation over microstructure of white matter integrity. In this study, we aim to study the white matter tracts, which are associated with normal ageing. 42 healthy subjects were included, which is composed of two groups. One is young subjects (age = 22.29±1.35), and the other is elder (age = 63.71±2.00). Statistical analysis over FA was carried out by TBSS. We observed FA decreases significantly in several white matter tracts, including anterior thalamic radiation (ATR), cingulum (cingulate gyrus), corticospinal tract (CST), forceps minor, forceps major, inferior longitudinal fasciculus (ILF), superior longitudinal fasciculus (SLF). Most found all tracts were reported in past literatures. Nevertheless, we are the first to find the relationship between forceps major and ageing.