Geographical Distribution Of Industry Driven Clinical Trials Performed For Leukemia Over The Last Ten Years.

JOURNAL OF CLINICAL ONCOLOGY(2016)

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摘要
2537Background: The incidence of leukemia (L) is increasing worldwide, with an estimated 350,000 people diagnosed each year. One major motivation for looking abroad for drug clinical development is the lowered cost of running a clinical trial in developing countries, about one-half to one-third that in a developed country. We aim to describe variations on the geographical distribution of industry driven clinical trials performed for L over the last 10 years (2005-2015). Methods: INC clinical trial database was reviewed for L, all types and compared to industry sponsored clinical trials listed on Trialtrove, 2015, Citeline database. The geographic location of the trial was classified based on the following countries: North America (NA), Western Europe (WE), Eastern Europe (EE), Latin America (LA), Middle East and North Africa (MENA) and Asia Pacific (AP). A single site within a region was considered positive for regional trial involvement. Geographic distribution of INC L trials was compared to geographic ...
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