Urine Ammonium And Preclinical Acidosis In Ckd

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY（2017）

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摘要

The kidney maintains the serum [HCO3−] at a normal value of 25 mEq/L by two distinct and highly regulated processes: ( 1 ) reabsorption of the filtered load of HCO3− and ( 2 ) production and excretion of ammonium (NH4+). Production of NH4+ is primarily a function of the proximal tubule, and

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关键词

Cell Signaling,acidosis,chronic kidney disease,chronic metabolic acidosis,complement

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