Predictors of Overall Survival (OS) in Patients with Multiple Myeloma (MM) Initiating First- and Second-Line Treatment in the Czech Republic

MM is a heterogeneous disease. The International Staging System (ISS) and the revised-ISS (R-ISS) can be used to stratify patients in terms of risk of mortality in newly-diagnosed MM (NDMM) however; there is less understanding of the predictors of OS in the relapsed setting. This retrospective analysis of the Registry of Monoclonal Gammopathies database, which covers ~80% of all Czech patients with MM, was designed to explore how predictors of OS differ between initiation of first- and second-line treatments, in order to further understand patient heterogeneity as the disease progresses.