Poly(lactide-co-glycolide) nanofibrous scaffolds chemically coated with gold-nanoparticles as osteoinductive agents for osteogenesis

•We designed and prepared a novel PLGA nanofibrous sheet for binding GNPs using a simple process.•The objective this study was to design a process for manufacturing PLGA-GNPs nanofibrous sheets which can be applied to biomaterials.•The biocompatibility and osteoinductive effect of PLGA-GNPs were demonstrated through in vitro test using a human adipose derived stem cells.•The developed scaffolds may be suitable as bone cell proliferation substrates for use in bone tissue engineering applications.