Curcumin-bortezomib loaded polymeric nanoparticles for synergistic cancer therapy

Sandra Medel,Zdenka Syrová,Lubomír Kováčik,Jiri Hrdy,Matúš Hornáček,Eliézer Jäger,Martin Hruby,Reidar Lund,Dušan Cmarko,Petr Stepanek,Ivan Raška,Bo Nyström

European Polymer Journal（2017）

引用 42|浏览24

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摘要

•Synthesized methoxy-poly(ethylene glycol)-block-polylactic acid (mPEG-b-PLA) copolymers.•Nanoparticles for drug delivery of bortezomib and curcumin.•Cell uptake and cytotoxicity have been tested on different breast cancer cell lines.

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关键词

Polymeric nanoparticles,Light scattering,Flow cytometry,Cellular uptake,Drug delivery

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