A Clinical And Histopathological Interpretation Of Lesions Of Tumours Of Hindgut

Sumit Gupta, Veena Saxena, Pragya Gupta,Krishna Dubey

JOURNAL OF EVOLUTION OF MEDICAL AND DENTAL SCIENCES-JEMDS(2016)

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摘要
We evaluated clinical and histopathological assessments of lesions of hindgut in our hospital.METHODSAll biopsies from surgically resected specimens of lower GIT tumors were included. Brief clinical history along with clinical findings was noted when the specimen was received. The specimen was then dissected and the gross features of the tumor were described. Standardized tissue bits were sampled from the tumor, surgical margins and lymph nodes if present.RESULTSThe most common symptom was bleeding per rectum, weakness, pain abdomen and constipation in the order 87%, 82%, 68%, 61.5% respectively. The commonest gross morphological features of neoplasms of lower GIT was ulceroproliferative growth 129/200 (64.5%) followed by polyp 71/200 (35.5%). The commonest location was anorectosigmoid region, colon, jejunum, ileum (48%, 39.5%, 7%, 5.5%) respectively. In resected specimens only 28 (14%) specimens showed lymph nodal metastasis and the commonest histological type was well differentiated adenocarcinoma (29%).CONCLUSIONHindgut lesions exhibited a wide spectrum of histopathological features, adenomatous polyp and well differentiated adenocarcinoma being most common among benign and malignant lesions.
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关键词
Benign, Malignant, Adenocarcinoma, Polyps, Hindgut Tumors
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