Investigations Of A New Diagnostics Technology For Hepatocellular Carcinoma Screening

JOURNAL OF CLINICAL ONCOLOGY(2015)

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摘要
e22171 Background: A newly developed diagnostic technology named Cancer Differentiation Analysis Technology (CDA) was investigated for hepatocellular carcinoma (HCC) screening. The CDA technology is a blood-sample based, multi-level, multi-parameter diagnostic method which detects signals from both proteins and cells, in which multiple aspects of information collected to improve diagnostic accuracy. Methods: Blood samples from patients with HCC (n = 511), cirrhosis (n = 71) and other benign liver diseases (BLD) (n = 46), as well as control subjects (n = 79) were collected in EDTA tubes. CDA values were measured using a CDA device. After removing outliers, the final valid CDA data came from 485 HCC patients, 64 cirrhosis, 44 other benign liver diseases, and 75 controls. All data were analyzed and the results were shown in the table below. Results: The average CDA of HCC, cirrhosis, BLD, and controls were 53.14, 44.04, 41.90, and 33.90 (rel. units), respectively. The results indicated that HCC could be sign...
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