Sequential Liver And Lung Resection For Colorectal Cancer Metastases: In Which Patients Should Surgery Be Proposed?

3524 Background: Resection of colorectal cancer (CRC) liver or lung metastases is an established therapeutic strategy. However, controversies exist when metastases are found concomitantly in both the organs or when the patients, who have undergone either liver or lung resection, have a recurrence in the other organ. Methods: All consecutive patients operated for CRC liver and lung metastasis (LLM) at our institution from January 1990 to December 2012 were reviewed. Our policy was to propose sequential surgery of both sites with perioperative chemotherapy, provided that the strategy was potentially curative. We aimed to evaluate Overall Survival (OS) of these patients, to develop a clinical usable prognostic score and to find out if cure is possible. Results: A total of 150 patients (89 men - 61 women; median age - 56 years) were included in the study. Median number of LLM resected was 3 and 1 respectively. Median follow-up was 5 years (Range 0.6 - 22.8 years). Median OS, 5-year OS and 10-year OS from firs...