739 Endoscopic Full-Thickness Resection: A Prospective Case Series From a Large Clinical Teaching Hospital in the Netherlands

Endoscopic full-thickness resection (eFTR) is an alternative to surgery for non-lifting or difficult-to-reach colorectal lesions in which other advanced techniques, like endoscopic mucosal resection (EMR) or endoscopic submucosal dissection, are not successful. In eFTR a clip is placed below the lesion prior to removing a circular transmural specimen. This allows en-bloc resection and determination of depth-of-invasion, without the risk of fecal spill. We aim to present our experiences with this device and evaluate eFTR indication, efficacy and safety.