High-avidity IgA protects the intestine by enchaining growing bacteria

NATURE(2017)

引用 346|浏览32
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摘要
Oral-vaccine-induced IgA cross-links growing bacteria into clonal aggregates, inhibiting pathogenesis, adaption and the spread of antimicrobial resistance genes.
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关键词
Antibodies,Bacterial pathogenesis,Evolutionary genetics,Inactivated vaccines,Mucosal immunology,Science,Humanities and Social Sciences,multidisciplinary
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