SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin

Jun Chen,Ming-Chao Zhong,Huaijian Guo,Dominique Davidson,Sabrin Mishel,Yan Lu,Inmoo Rhee,Luis-Alberto Pérez-Quintero,Shaohua Zhang,Mario-Ernesto Cruz-Munoz,Ning Wu,Donald C. Vinh,Meenal Sinha,Virginie Calderon,Clifford A. Lowell,Jayne S. Danska,André Veillette

NATURE（2017）

引用 179|浏览23

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摘要

The identification of homotypic SLAMF7 interactions responsible for haematopoietic tumour cell phagocytosis by macrophages when the inhibitory receptor/ligand interaction of SIRPα/CD47 is blocked therapeutically.

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关键词

Immunology,Immunotherapy,Science,Humanities and Social Sciences,multidisciplinary

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