Metabolic engineering of Bacillus sp. for diacetyl production

Wenbo Hao,Fangling Ji,Jingyun Wang,Yuepeng Wang,Yue Zhang,Yongming Bao

Process Biochemistry（2017）

引用 10|浏览14

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摘要

•We show high-yield production of diacetyl by Bacillus sp.•We improved diacetyl production by blocking ALDC in Bacillus sp.•Diacetyl biosynthetic pathway was amplified by overexpressing ALS in Bacillus sp.•Fe3+ enhanced the NOD of α-acetolactate to diacetyl in the engineered Bacillus sp.

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关键词

Bacillus,Diacetyl,Metabolic engineering,Acetoin,α-Acetolactate decarboxylase,α-Acetolactate synthase

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