Cultured trophoblasts are salt-sensitive with Na+ and Cl- transporters differentially expressed in placenta and kidney of rats upon salt exposure

Previously, we and other demonstrated that in pregnancy enhanced intake of NaCl does lower maternal blood pressure and improves pregnancy outcome for yet unknown reasons. As non-renal targets respond to Na+ exposure such as dendritic skin cells, we hypothesized that trophoblasts react upon being Na+-challenged with favourable responses.