Simultaneous determination of tryptophan and 8 metabolites in human plasma by liquid chromatography/tandem mass spectrometry

Lysiane Boulet,Patrice Faure,Patrice Flore,Julien Montérémal,Véronique Ducros

Journal of Chromatography B（2017）

引用 58|浏览7

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摘要

•A quantitative method to simultaneously assay tryptophan and 8 metabolites in plasma.•The method is quick (15min per chromatographic run) and simple.•The method has been validated according to NF EN ISO 15189 criteria.

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关键词

Tryptophan,Kynurenine,Anthranilic acid,3-hydroxykynurenine,5-hydroxytryptophan,Serotonin

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