Synthesis and characterization of some analogues of Febuxostat - An anti-hyperuricemia drug

Febuxostat is indicated use for the treatment of hyperuricemia and gout. During the process development of Febuxostat, ten process related analogues were observed at a level of 0.1-0.15 area percent. Synthesis and characterization of these analogues and investigation of the root cause of their formation is described.