Early Stage Ovarian Cancer Clinical Behavior According To Figo 2014 Staging Changes With A Focus On Ic Subtype: Data From Prospective Geico Registry.

5554 Background: Early stage ovarian cancer (ESOC) represents 10-15% of all Ovarian Cancer (OC) cases and most frequent ESOC substage (IC) has undergone major changes in FIGO 2014 staging. Methods: A centralized prospective registry of ESOC (I-IIb) patients treated at GEICO (Spanish Group of Ovarian Cancer Research) centers was initiated on January 1998 and updated up to November 2014. We aim at prospectivley explore both the robustness of FIGO in ESOC and the role of ascites in terms of prognosis. We analyze FIGO 2014 stage IA-IB (1), IC1+IC2 (2), IC3 citology positive in washing (3) or in ascites (4) and IIA-B (5). Results: A total of 1,178 cases with a median age of 53 yrs. (16-97 yrs) have been included. Histology distribution according to Kurman (Int J Gynecol Pathol 2008) showed type I 65.5% and type II 34.5%, grade 1 23.6%, grade 2 21.4% and grade 3 45%. Distribution of ESOC stages, frequency and Relapse Free Survival (RFS) and Disease Specific Survival (DSS) are summarized in table 1; subclassific...