Fruitful steps in the prevention of chemotherapy-induced nausea and vomiting (CINV) over the past 30 years: A historical comparison of patients enrolled in clinical trials during different antiemetic times

    Journal of Clinical Oncology, 2017.

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    Abstract:

    e20685 Background: Chemotherapy-induced nausea and vomiting (CINV) was among the most frustrated side effects of cancer treatment. Over the past 30 years, several types of agents have been introduced to prevent CINV and gradually made Setrons (5HT3RA), Dexamethasone (DXM) and NK-1 receptor antagonists (NK-1RA) the cornerstones of antiemet...More

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