Preparation of highly functionalized 1,5-disubstituted tetrazoles via palladium-catalyzed Suzuki coupling

Edward J. Hennessy,Mark Cornebise,Lakshmaiah Gingipalli,Tyler Grebe,Sudhir Hande,Valerie Hoesch,Hoan Huynh,Scott Throner,Jeffrey G. Varnes,Ye Wu

Tetrahedron Letters（2017）

引用 10|浏览29

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摘要

•A variety of 1,5-disubstituted tetrazoles have been synthesized.•Substrates readily prepared from azides and p-toluenesulfonyl cyanide.•Pd-catalyzed Suzuki conditions compatible with many functional groups.

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关键词

Tetrazoles,Heterocycles,Suzuki coupling,Biologically-active Molecules

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