CENTRAL OBESITY PREDICTS CIRCULATING PROGENITOR CELL LEVELS

Jay Khambhati,Pratik Sandesara,Ayman Samman Tahhan,Matthew Topel,Frank Corrigan,Heval Mohamad Kelli,Eric Stahl,Marc Allard-Ratick,Ayman Alkhoder,Hiroshi Aida,Mohamad Mazen Gafeer,Iraj Hesaroieh, Ernestine Mahar,Edmund K. Waller,Viola Vaccarino,Thomas R. Ziegler,Laurence Sperling,Kenneth L. Brigham,Greg S. Martin,Arshed A. Quyyumi

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2017）

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摘要

Background: Obesity is a pro-inflammatory state leading to endothelial cell injury and dysfunction. In particular, central (android) obesity is associated with increased cardiovascular disease risk. Bone marrow derived CD34+ progenitor cells (PC) levels are elevated in patients with high body mass

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