INFLUENCE OF LOW VERSUS HIGH DOSE ON THE ASSOCIATION OF LOOP DIURECTIC AND MORTALITY IN PATIENTS WITH HEART FAILURE: INSIGHTS FROM THE UNITE-HF REGISTRY

Kirkwood F. Adams,Stephanie H. Dunlap, Amanda Lee,Ileana Pina,Adrian Van Bakel,J. Herbert Patterson,Todd A. Schwartz,Frank McGrew,Hector Ventura,Ron Oren

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2017）

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摘要

Background: Loop diuretics are associated with a dose-related increase in mortality in patients (Pts) with heart failure (HF) but less is known about the pattern of this relationship.Methods: The relationship between low and high doses of loop diuretic and mortality was investigated in the UNITE-

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