The Fam-Gem-1 Study: Frequency And Characteristics Of Familial Melanoma In Spain.

9039 Background: Melanoma risk is determined by environmental, phenotypical and familial background. Literature describes a 5-10% of melanoma cases in a familial setting. Familial melanoma (FM) is classically defined as u003e2 first degree relatives with melanoma in a family. Multiple melanomas (MM), pancreatic cancer (PC) in family and multiple nevi are also risk criteria. In Spain, there are several local studies about epidemiology and characteristics of FM, but there are no studies exploring all the territory Methods: FAM-GEM-1 is a national, observational, 2 years-registry study (2011-2013), conducted by the Spanish Multidisciplinary Melanoma Group (GEM), whose principal objective was to assess the rate of patients with FM in Spain. Secondary objectives were to analyze if FM patients are different in terms of clinical, pathological and/or molecular features; and to create a registry of FM for further studies. We present the final results of the 1,049 patients registered. Results: In Spanish population, ac...