Uterine Tumors Resembling Ovarian Sex Cord Tumor (Utrosct): 4 Cases Report And Literature Review

Uterine tumors resembling ovarian sex cord tumor (UTROSCT) is an extremely rare type. It is currently distinguished from endometrial stromal tumors with sex cord-like element (ESTSCLE). We reported four cases recently with UTROSCT to describe the histological morphology, immunophenotype, and clinical behavior. During July, 2014 and Dec, 2015, two patients underwent surgical treatment respectively at Tianjin Medical University Cancer Institute & Hospital and Tianjin Central Hospital of Gynecology Obstetrics, the other two were consultant cases. Hematoxylin & Eosin and Immunohistochemical staining were performed. The sections were reviewed by three independent pathologists to confirm the diagnosis. Four patients with an age range of 35 to 80 years underwent the surgical treatment for UTROSCT. And the biopsy specimen was sent for histopathology and immunohistochemistry. Besides, genes were examined in the two cases, gene fusions of JAZF1-SUZ12 was not detected and FOXL2 gene mutation was also not found. UTROSCTs are polymorphic neoplasms with true sex cord differentiation. Generally, the primary management strategy remains surgical.