Network Optimization of Functional Connectivity Within Default Mode Network Regions to Detect Cognitive Decline

The rapid aging of the world's population is causing an increase in the prevalence of cognitive decline and degenerative brain disease in the elderly. Current diagnoses of amnestic and nonamnestic mild cognitive impairment, which may represent early stage Alzheimer's disease or related degenerative conditions, are based on clinical grounds. The recent emergence of advanced network analyses of func...