The immunomodulatory activity of SerpinB3 an protease-inhibitor in vivo and in vitro

A. Cappon,G. Villano,S. Quarta,Alessandra Biasiolo,C. Turato,M. Ruvoletto,S. Sutti,S. Bruzzì,E. Novo,E. Morello,S. Cannito,Emanuele Albano,Maurizio Parola,Patrizia Pontisso

Digestive and Liver Disease（2017）

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摘要

Introduction: NASH is associated with a higher risk of overall mortality and HCC development. The serin protease inhibitor SerpinB3 is not expressed in normal liver, but its level increases in relation with the extent of liver damage. To date, only few data are available on this serpin in the setting of NASH.

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Protease Inhibition

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