Bone Effects Of Adjuvant Tamoxifen (T), Letrozole (L), Or L Plus Zoledronic Acid (Z) In Early Breast Cancer (Ebc): The Phase Iii Hoboe Study

F. Perrone,Ciro Gallo,Secondo Lastoria,F. Nuzzo,A. Gravina,G. Landi,E. Rossi,Carmen Pacilio,V. Labonia, F. Di Rella,M. De Laurentiis,M.C. Piccirillo,M. Di Maio,Pasqualina Giordano,Gennaro Daniele,G. De Feo, R. Fiore,Simona Signoriello,Giuseppe Esposito,A. De Matteis

JOURNAL OF CLINICAL ONCOLOGY（2011）

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摘要

517 Background: Treatment with L can reduce bone mineral density (BMD) in patients (pts) with EBC. However, the addition of Z may protect against bone loss. Methods: We performed a 1:1:1 randomized...

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关键词

adjuvant tamoxifen,bone effects,early breast cancer,breast cancer,zoledronic acid

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