Intestinal epithelial cells under endoplasmic reticulum stress boosts serine proteolytic activity and modulates barrier function

N. Sola Tapias,A. Denadai-Souza, C. Rolland-Fourcade,C. Blanpied,G. Dietrich,C. Bonnart,A. Edir,C. Rolland,C. Deraison,N. Vergnolle,F. Barreau

Journal of Crohns & Colitis（2017）

引用 2|浏览8

暂无评分

摘要

Background: Studies on ulcerative colitis (UC) patients show an excessive induction of endoplasmic reticulum stress (ERS) in intestinal epithelial cells (IEC) of the colonic mucosa, leading to intestinal barrier disruption and inflammation. Moreover, the secretion of serine proteases from IEC is enh

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要