Decursin and decursinol angelate-rich Angelica gigas Nakai extract suppresses de novo lipogenesis and alleviates nonalcoholic fatty liver disease and dyslipidemia in mice fed a high fat diet

•Decursin and decursinol angelate are main constituents of Angelica gigas Nakai extract.•Angelica gigas Nakai extract supplementation prevents HFD-induced NAFLD development.•Angelica gigas Nakai extract activates Sirt1-AMPK pathway.