Reply: Did Mutation Type Affect the Efficacy of Mexiletine Observed in Patients With LQTS Type 3?

Andrea Mazzanti,Riccardo Maragna,Carlo Napolitano,Silvia G. Priori

Journal of the American College of Cardiology（2017）

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We thank Dr. Hameed for his question, and we are happy to share this information. Two of the 3 infants who continued to experience arrhythmic events while receiving mexiletine were carriers of SCN5A mutations previously characterized in vitro by our group and predicted to be insensitive to

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