Evaluation of multiplex assay platforms for detection of influenza hemagglutinin subtype specific antibody responses

Zhu-Nan Li,Kimberly M. Weber, Rebecca A. Limmer, Bobbi J. Horne,James Stevens, Joy Schwerzmann,Jens Wrammert,Megan McCausland,Andrew J. Phipps,Kathy Hancock,Daniel B. Jernigan,Min Z. Levine,Jacqueline M. Katz,Joseph Miller

Journal of Virological Methods（2017）

引用 9|浏览27

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摘要

•Platforms were developed to detect subtype-specific antibody responses to influenza.•These platforms are suitable for areas where multiple viruses co-circulate.•Specificity differs in persons “exposed” versus “un-exposed” to heterosubtypic HAs.•HA with the highest fold rise correlates with correct exposed influenza antigen.

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关键词

Influenza,Hemagglutinin,Antibody,Chembio,Luminex®,Antibody biosensor assay

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