O-028 Opercular Index Score (OIS): A Novel Predictor of Collateral Robustness and Neurologic Outcomes in the Endovascular Management of Acute Ischemic Stroke

Purpose Assessment of collaterals is imperative in patient selection for endovascular reperfusion in acute ischemic stroke (AIS). The purpose of this study was to evaluate the correlation between a novel CTA based collateral scoring system: the Opercular IndexScore (OIS), with the capillary index score (CIS) at angiography and neurologic outcomes at 90 days following endovascular treatment of acute ischemic stroke. Materials and methods Data from 58 patients with AIS who underwent clinical assessment, institutional stroke based CT imaging (noncontrast CT, CT Perfusion with CTA reconstructions) and endovascular reperfusion were included in this study. OIS was retrospectively calculated from CTA images as the ratio of the number of opacified branches in the Sylvian fissure on the normal side to those on the affected side and dichotomized into favorable OIS (fOIS i.e. OIS ≤ 2) and poor OIS (pOIS i.e. OIS u003e 2). CIS was defined as favorable (CIS ≥ 2) or unfavorable (CIS Results Thirty-five patients had fOIS and 20 patients had pOIS. There was no difference in mean age (p = 0.96), gender (p = 0.31), side of occlusion (p = 0.11), use of IV-tPA (p = 0.73), ASPECTS (p = 0.61), door-to-puncture time (p = 0.49), door to recanalization time (p = 0.81), recanalization rate (0.32) or TICI scores (p = 0.78). There was a trend towards lower NIHSS in the fOIS group (p = 0.07). At angiography, 82.9% of patients (n = 29) with fOIS had a fCIS and 40.0% of patients (n = 14) with pOIS group had a fCIS (p = 0.002). Patients with fOIS had an 80.0% (n = 28) rate of good neurological outcomes compared to 15.0% (n = 3) in the pOIS group (p Conclusion OIS is a practical, noninvasive scoring system that can be used to predict collateral robustness and good clinical outcome among patients undergoing endovascular recanalization in the treatment of acute ischemic stroke. Disclosures A. Copelan: None. M. Chehab: None. S. Xli: None. W. Brinjikji: None. Z. Wilseck: None. D. Kallmes: None. J. Wilseck: None.