An Iterative Locally Auto-Weighted Least Squares Method for Microarray Missing Value Estimation

Microarray data often contain missing values which significantly affect subsequent analysis. Existing LLSimpute-based imputation methods for dealing with missing data have been shown to be generally efficient. However, all of the LLSimpute-based methods do not consider the different importance of different neighbors of the target gene in the missing value estimation process and treat all the neigh...