Protection of flavonoids from Smilax china L. rhizome on phenol mucilage-induced pelvic inflammation in rats by attenuating inflammation and fibrosis

Luyao Song,Liwen Tian,Yun Ma,Yang Xie,Haixing Feng,Fei Qin,Liqian Mo,Si Lin,Lianbing Hou,Chunxia Wang

Journal of Functional Foods（2017）

引用 23|浏览11

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摘要

•The chemical compositions of FSCR were analysed by UPLC-PDA-MS.•A PID model induced by phenol mucilage was successfully established in rats.•The effects of FSCR on rats with PID were studied.•FSCR attenuated pelvic inflammation and prevented fibrosis.•The ERK1/2 and Smad2/3 signalling pathways may be involved in the effects of FSCR.

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关键词

Chlorogenic acid (PubChem CID: 1794427),Astilbin (PubChem CID: 119258),Isoastilbin (PubChem CID: 9981176),Quercetin-3-O-α-l-rhamnopyranoside (PubChem CID: 5280459),Cinchonain Ia (PubChem CID: 10456516),Engeletin (PubChem CID: 6453452),Isoengeletin (PubChem CID: 101937309)

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